Positions a and d of the GCN4 zipper motif are filled by Val and Leu residues, respectively, except for one Asn at position a, which forms an asymmetric hydrogen bond across the dimer interface.

Carboxylic acids are ubiquitous in bioactive organic molecules and readily available chemical building blocks. Carboxylic ...

B71, 164-175; doi: 10.1107/S205252061500270X], point out that until now there has been no exhaustive classification of these carboxyl(ate) motifs present in crystal structures, despite their ...

Focusing on the laminating polymer phase, they designed a low-molecular-weight polymer with low glass-transition temperature, which was equipped with varying degrees of a supramolecular binding motif.

Back to Basics. Hydrogen is one of the most common elements in the world — making up 75 percent of all visible matter and more than 90 percent of all the atoms in the universe. At the same time ...

Chemistry students the world over are familiar with covalent bonds and hydrogen bonds. Now a study has revealed a strange variety of bond that acts like a hybrid of the two.

Assembling Smallest Prussian Blue Analogs Using Chiral Hydrogen Bond-Donating Unit toward Complete Phase Transition. Journal of the American Chemical Society , 2024; 146 (35): 24238 DOI: 10.1021 ...

Hydrogen-bonding pairing regulates protein-ligand affinity; helps improve drug design. Infections with bacterium Clostridium difficile have rapidly become a significant medical problem in ...