U.S. Immigration and Customs Enforcement officers conducted a series of raids across “multiple locations” in Los Angeles on Friday, reportedly taking dozens of people into custody while facing off with demonstrators.

Immigration and Customs Enforcement arrested 72 people at a nightclub that the agency claims is run by a cartel member in Charleston, South Carolina. The Department of Homeland Security released a statement saying that the club was run by “a suspected member of the Los Zetas Cartel.

The FBI confirmed it’s participating in the HSI raids, not just in Los Angeles but nationwide, “as directed by the Attorney General.”