Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that ...

It's well known that exercise is good for health and helps to prevent serious diseases, like cancer and heart disease, along ...

Pancreatic cancer has long been one of the deadliest malignancies in medicine, largely because it is usually detected late ...

Globally, metabolic dysfunction-associated steatotic liver disease (MASLD) is now the most common chronic liver disease, affecting up to one in three people in the general population, with an ...

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

A new proteomic analysis is shedding a fresh light on the cytokine networks fueling idiopathic pulmonary fibrosis (IPF), ...

Discover how strategic reductions in dietary protein can trigger powerful cellular repair pathways, lower pro-aging signals, and potentially extend healthspan without the demands of chronic calorie ...

Pancreatic cancer has a reputation for being one of the deadliest malignancies, in part because it is often diagnosed late and progresses quickly. While genetics and age play a role, a growing body of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In early-stage estrogen receptor-positive (ER ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In this manuscript, ...