Putting this together, 46XX refers to a female and 46XY defines a male. Klinefelter syndrome is a trisomy condition, referring to a condition in which three, rather than two of the autosomal ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study. Down syndrome is caused by the presence of a third copy ...

Trisomy 21, the genetic cause of Down syndrome, disrupts primary cilia formation and function, in part through elevated Pericentrin, a centrosome protein encoded on chromosome 21. Yet how trisomy 21 ...