According to the company's statement, these medications are designed to improve glycemic control in adults with Type 2 Diabetes while also reducing cardiovascular outcomes in the patients.

Pediatric doses associated with consistent exposure across age are still unknown. Therefore, we aim to identify a dosing strategy for ivermectin treatment in both pre-school-aged children (2–5 years ...

In 1996, the Food and Drug Administration approved the labeling for metformin (dimethylbiguanide), the only biguanide currently available in the United States. Phenformin, the other previously ...

We hypothesized that administration of cimetidine, an Oct/Mate inhibitor, will result in increased plasma levels and decreased renal clearance of metformin and endogenous Oct/Mate substrates in rats.

Note: This article describes typical dosages for Zepbound provided by the drug’s manufacturer. When receiving Zepbound, always follow the dosage prescribed by your doctor. Zepbound comes as a ...

9. van Dalem J, Brouwers MC, Stehouwer CD, et al. Risk of hypoglycaemia in users of sulphonylureas compared with metformin in relation to renal function and sulphonylurea metabolite group: population ...

Patients were designated as users of certain drugs if they refilled the prescription for the 80% of the required dosage or more ... we prove that metformin may have benefits related to reducing ...

In the future, metformin dose and duration should be well-defined, and use GDF-15 as a biomarker of metformin-induced weight loss will have to be confirmed. Moreover, the clinical implication and use ...