Shepherd’s purse offers a compelling blend of hemostatic, anti-inflammatory, and antioxidant properties supported by its rich ...
The emergence of disease-modifying therapies has transformed the management of spinal muscular atrophy (SMA), shifting care from palliative approaches toward proactive, intervention-based strategies.
Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
This study provides valuable findings that MK2 inhibitor CMPD1 can inhibit the growth, migration and invasion of breast cancer cells both in vitro and in vivo. The evidence supporting the claims of ...
GSK-3179106 reduces inflammation and acute lung injury in mice through p38 MAPK targeting Nov. 29, 2024 ...
Phosphorylation of p38 MAPK, ERK, and JNK was measured by Western blotting with phosphospecific (phospho-) p38 MAPK, phospho-ERK, or phospho-JNK antibodies, as described previously. 26 The same ...
The KC-135 heritage jet will remain in service with its WWII-inspired paint scheme until 2025. The Nebraska Air National Guard’s 155th Air Refueling Wing (ARW) unveiled a historic KC-135R Stratotanker ...
Shanghai Meiyue Biotech Development Co. Ltd. has discovered MAPK p38 inhibitors reported to be useful for the treatment of arthritis, psoriasis, systemic lupus erythematosus, diabetes, cancer, ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Macrophages sense pathogens and orchestrate ...
Androgen Receptor (AR) activity in prostate stroma is required to maintain prostate homeostasis. This is mediated through androgen-dependent induction and secretion of morphogenic factors that drive ...
Bosentan, a prescribed vasodilator, improves cardiac function but enhances viral load and myocarditis severity through ETRA mediated p38 MAPK activation; p38 MAPK is a desirable antiviral target.
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