Researchers say this is the first combination therapy that targets two different cancer survival mechanism: PARP and WNT signaling.
Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope ...
Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome ...
A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate ...
Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...
Fruit color transformation involves chlorophyll degradation, a key process determining ripening quality. Ethylene is known to trigger chlorophyll breakdown, while light can either promote synthesis or ...
Wnt signaling pathways have many important roles in cells and are highly conserved across the animal kingdom from fruit flies to humans. In addition to Wnt signaling being involved in many processes ...
Nutrient surplus sensing through PI3K (phosphoinositide-3-kinase) and mTOR (mechanistic target of rapamycin) stimulates anabolism to expand cellular mass, whereas nutrient and energy deprivation ...
Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and it has an unclear pathogenesis and lacks validated, specific biomarker-based diagnostic approaches, ...
Cardiovascular disease poses a significant risk to human health and remains the leading cause of illness and death globally, with its incidence continuing to rise. The intricate pathophysiological ...
Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a new study. The paradox of enhanced memory despite sleep loss could be explained ...