A type 2 diabetes drug, pioglitazone, may reduce the risk of prostate cancer relapse by targeting the PPARγ protein Prostate cancer patients with diabetes on PPARγ drugs had no relapse during ...

PPARγ plays a regulatory role in lipid metabolism, insulin sensitivity and inflammatory responses. In diabetes treatment, drugs like pioglitazone activate this receptor to improve glucose control. The ...

For more than 20 years, the protein has been the target of certain medications, including so-called thiazolidinediones such as pioglitazone, which are used to treat type 2 diabetes.

For more than 20 years, the protein has been the target of certain medications, including so-called thiazolidinediones such as pioglitazone, which are used to treat type 2 diabetes.

Scientists from Chiba University in Japan and other institutions have discovered that the drug pioglitazone, commonly used to treat diabetes, may help prevent painful skin ulcers in people with ...

The research suggests that pioglitazone’s ability to reduce inflammation helps wounds heal faster and prevents ulcers from forming. However, since the drug can cause side effects, like weaker ...

The safety of prescription drugs and their adverse effects, however rare, are a source of great debate. 1, 2 In an article published in JAMA, Lewis et al. 3 examined the use of pioglitazone and ...

Actos (pioglitazone) is a prescription drug that’s used to treat type 2 diabetes. This drug can interact with other medications and some supplements. For example, Actos can interact with certain ...

Upon analysis, researchers found 8.3% of the people taking pioglitazone developed dementia, compared to the 10% of people with type 2 diabetes who did not take the drug.

Link Between Diabetes Drug Pioglitazone and Dementia During the trial, 8.3% of those who took pioglitazone acquired dementia, compared to 10.0% of those who did not.

Overall, incidence of dementia fell by 16 percent among participants prescribed the drug. Interestingly, the longer the patients took pioglitazone, the lower their risk was.

Researchers are saying the drug pioglitazone may help reduce the risk of dementia. The medication, sold under the brand name Actos, is prescribed to treat type 2 diabetes. Experts say a healthy ...