Blastic plasmacytoid dendric cell neoplasm (BPDCN) is a rare, aggressive blood cancer that often involves the bone marrow, skin and, sometimes, lymph nodes. First-in-class antibody-drug conjugate ...

Background: BPDCN is a rare, clinically aggressive hematological malignancy primarily involving the skin, bone marrow, and lymph nodes. CD123 (IL-3Rα) is highly overexpressed on the surface of all ...

The purpose of this guideline is to update the ASCO evidence-based recommendations on the use of sentinel lymph node biopsy (SLNB) in early-stage breast cancer. ASCO first published a practice ...

An expert discusses how treatment selection in blastic plasmacytoid dendritic cell neoplasm (BPDCN) involves balancing disease-specific targeting and patient fitness, with tagraxofusp remaining the ...

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a type of blood cancer that affects immune system cells. It most often affects the skin but can also involve bone marrow and other cell types.

In some experiments, pDCs were collected for assessing the capacity to promote the differentiation of naïve CD4 T lymphocytes. In vitro pDCs stimulated with CSE-induced NETs were cocultured with naive ...

However, many individuals neglect this essential system, leading to various health issues. Enter Lymph Savior, a remarkable daily supplement designed specifically to support lymphatic wellness.

What you see is there's a large discrepancy. For example, around 8% or 9% of patients are thought to have cancer in their lymph nodes prior to surgery. When patients with plasmacytoid cancer undergo ...

Background Type 1 interferons (IFN-1) are major drivers of disease activity in systemic (SLE) and cutaneous lupus erythematosus (CLE). Plasmacytoid dendritic cells (pDCs) are the major producers of ...

A swollen lymph node can be a bit like your body’s version of a red flag: When one of these bean-shaped clusters of immune cells in your neck, armpit, or groin puffs up, it’s typically an ...

Summary: Plasmacytoid dendritic cells (pDCs) represent a specialized subset of dendritic cells (DCs) known for their role in producing type I interferons (IFN-I) in response to viral infections. It ...