Since the technique was first published in 2019, prime editing has grown with lightning speed, alongside hopes for what it can achieve. Emilie is an assistant editor at the Scientist. She has a ...

Continue reading about off-target effects in this story. Base and Prime Editing Offer Precision CRISPR-based systems that rely on traditional Cas nucleases like Cas9 cut through both strands of DNA ...

to initiate trials of the first-ever prime editing drug. The FDA cleared Prime Medicine’s investigational new drug (IND) application for PM359 for the treatment of chronic granulomatous disease ...