INTRODUCTION Ocular surface squamous neoplasia (OSSN) is an entity that comprises the spectrum of squamous neoplasia of the conjunctiva and cornea, which includes conjunctival intraepithelial ...

The article by McKelvie et al 1 is especially noteworthy as it highlights a number of interesting observations. In the first instance, the authors highlight that conjunctival squamous cell carcinoma ...

Description OSSN includes a spectrum of corneal and conjunctival lesions from dysplasia and carcinoma in situ, typically termed conjunctival or corneal intraepithelial neoplasia, to squamous cell ...

Brownish areas are regarded as a red-flag sign for esophageal neoplasia, and their importance in the screening of esophageal neoplasias has been confirmed in previous studies. [ 9, 10, 12, 13, 15 ...

Risk factors for cutaneous squamous cell carcinoma recurrence, metastasis, and disease-specific death: a systematic review and meta-analysis. JAMA Dermatol. 2016;152 (4):419-428. doi:10.1001 ...

Colonoscopy screening at age 45 yields neoplasia rates close to older adults: Study supports guideline change by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Robert Egan Editors' notes ...

Traws Pharma published promising data on rigosertib for treating RDEB-associated SCC, showing an 80% response rate in clinical trials. The company is actively seeking development and ...

Anal intraepithelial neoplasia (AIN) Anal intraepithelial neoplasia (AIN) means there are abnormal cells in the lining of your anus. AIN is not cancer but the cells might develop into cancer in the ...

Background: The standard of care (SOC) over the past two decades for resected locally advanced SCCHN (LA-SCCHN) with high-risk of relapse is adjuvant cisplatin-radiotherapy (CRT). Despite these ...

A total of 363 participants (234 with a CPS of ≥10 and 347 with a CPS of ≥1) were assigned to the pembrolizumab group and 351 (231 with a CPS of ≥10 and 335 with a CPS of ≥1) to the ...

Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of ...