NFL draft guru Mel Kiper Jr. and league insider Field Yates went back-and-forth making selections throughout a three-round mock. In that area of the draft, the Buffalo Bills enter the event with three picks. The top one is in Round 1 at No. 30 overall. The two others are in the second round at No. 56 and 62.

In our latest 2025 NFL mock draft from Christian D'Andrea, he had the Colorado QB dropping out of the top-three -- he had the Giants trading out of the No. 3 spot -- and landing with the New Orleans Saints, who trade up to No. 4 for Sanders.

Some fans and NFL analysts loved Colorado Buffaloes quarterback Shedeur Sanders so much heading into the 2025 NFL Draft that they called for him to go off the board at No. 1 to the Tennessee Titans. This prediction couldn’t have been further from the truth,