gut.bmj6d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
gut.bmj11h
Pathology of idiopathic megarectum and megacolon
Background—The aetiology and pathology of both idiopathic megarectum and idiopathic megacolon are unknown. In particular, it is unknown whether there are abnormalities involving enteric nerves or ...
gut.bmj20h
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways
2 Microbiology and Tumour Biology Centre, Karolinska Institute, Stockholm, Sweden 3 Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden 4 Microbiology and Tumour ...
gut.bmj1d
P207 Effects of fluconazole, gemfibrozil, and rifampin on the pharmacokinetics, safety, and tolerability of etrasimod
Introduction Etrasimod (ETR), a once-daily (QD), oral, selective sphingosine 1-phosphate receptor modulator in clinical development for immune-mediated inflammatory disorders, is a substrate of ...
gut.bmj3d
Pathophysiology of functional dyspepsia
Functional dyspepsia is a symptom complex characterised by postprandial upper abdominal discomfort or pain, early satiety, nausea, vomiting, abdominal distension, bloating, and anorexia in the absence ...
gut.bmj3d
Measurement of normal portal venous blood flow by Doppler ultrasound.
Department of Medical Physics, Bristol and Weston Health Authority. The volume flow rate of blood in the portal vein was measured using a duplex ultrasound system. The many errors inherent in the ...
gut.bmj5d
Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome
Correspondence to Dr G Nicholas Verne, Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112-2699, USA; gverne{at}tulane.edu Background More effective treatments are ...
gut.bmj6d
Intestinal reticulosis as a complication of idiopathic steatorrhoea
Three patients who had idiopathic steatorrhoea associated with reticulosarcoma of either the jejunum or the ileum are described. Previously reported cases with these features are reviewed and the ...
gut.bmj6d
Protective effect of metronidazole on uncoupling mitochondrial oxidative phosphorylation induced by NSAID: a new mechanism
a Department of Gastroenterology, University of São Paulo (USP) Medica1 School, São Paulo, Brazil, Laboratory of Medical Investigation (LIM 07), General Clinics Hospital of the USP Medical School, b ...
gut.bmj4d
MRE combined with FIB-4 (MEFIB) index in detection of candidates for pharmacological treatment of NASH-related fibrosis
Correspondence to Professor Rohit Loomba, NAFLD Research Center, Division of Gastroenterology and Hepatology, Department of Medicine, University of California San Diego, La Jolla, California, USA; ...
gut.bmj2d
IDDF2024-ABS-0043 Alistipes putredinis alleviates murine experimental colitis through 2-methylbutyric acid-mediated immune tolerance
Background While Alistipes putredinis (AP) abundance in the faeces of patients with inflammatory bowel disease (IBD) decreases, its role in IBD is not well understood. We, therefore, investigated the ...
gut.bmj3d
PMO-040 The development and validation of a nutritional prioritising tool for use in patients with chronic liver disease
Introduction Patients with cirrhosis are frequently malnourished and this has a detrimental effect on outcome in terms of complications, survival after liver transplantation and overall liver-related ...