The growth rate of the atmospheric abundance of methane (CH 4) reached a record high of 15.4 ppb yr −1 between 2020 and 2022, but the mechanisms driving the accelerated CH 4 growth have so far been ...

Many cities seek to alleviate extreme heat via planting trees. However, the cooling achieved by such programs is debated because previous analyses address scales much smaller than the whole-city scale ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium (III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...

Self-reproduction is one of the most fundamental features of natural life. This study introduces a biochemistry-free method for creating self-reproducing polymeric vesicles. In this process, ...

We show that for thousands of years, humans have concentrated in a surprisingly narrow subset of Earth’s available climates, characterized by mean annual temperatures around ∼13 °C. This distribution ...

Significance Increasing species richness toward the equator has been hypothesized to result from elevated temperatures, which increase molecular rates and consequently facilitate rapid speciation. We ...

Healthy brain function requires a delicate balance of neural excitation (E) and inhibition (I). In animals, this balance—the E/I ratio—is known to decrease with the maturation of inhibitory circuitry ...

Meiotic recombination is an evolutionary-conserved process that shapes genetic variation in most eukaryotes. DNA is packaged into nucleosomes, and high levels of nucleosome occupancy suppress ...

The Merovingian period (5th to 8th cc AD) was a time of demographic, socioeconomic, cultural, and political realignment in Western Europe. Here, we report the whole-genome shotgun sequence data of 30 ...

Bispecific T cell engagers (TcEs) that are able to simultaneously bind to epitopes on cancer cells and T cells are a versatile, highly potent, and economical immunotherapeutic tool (1). TcEs are ...

F-type ATP synthase (F 1 F O) catalyzes proton motive force-driven ATP synthesis in mitochondria, chloroplasts, and bacteria. We have identified an architecture of F 1 F O from Chloroflexus ...

The known calcium hydrides have a stoichiometry of CaH 2 at ambient pressure. Here, we explored other calcium hydrides with larger hydrogen contents by compressing a mixture containing Ca + hydrogen ...