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All submissions to BMJ Case Reports require the completion of author statements. Case reports should have a maximum of four authors. One of the co-authors should be the lead clinician responsible for the patient’s care and responsible for the integrity of the content of the case report, signed informed consent and author statements accompanying each manuscript.
Clinical course of a 66-year-old man with an acute ischaemic …
A 66-year-old man was admitted to hospital with a right frontal cerebral infarct producing left-sided weakness and a deterioration in his speech pattern. The cerebral infarct was confirmed with CT imaging. The only evidence of respiratory symptoms on admission was a 2 L oxygen requirement, maintaining oxygen saturations between 88% and 92%. In a matter of hours this patient developed a greater ...
Amlodipine induced gingival enlargement | BMJ Case Reports
There are both inflammatory and non-inflammatory mechanisms involved. The accumulation of the drug in the gingival crevicular fluid in the presence of bacteria can lead to upregulation of proinflammatory cytokines leading to gingival enlargement.3 Even decreased folic acid uptake leads to defective collagenase activity, increased adrenocorticotrophic hormone due to feedback from adrenal cortex ...
Tuberculous meningitis - BMJ Case Reports
A 22-year-old Nepali man presented with intermittent confusion, fever, unsteadiness and a 10 kg weight loss over 1 month. His chest radiograph was as shown (figure 1). Lumbar puncture showed an opening pressure of 28 cmH2O, white cell count 30×109/L; lymphocytes 20, neutrophils 10×109/L, protein 0.9 g/L. Gram stain showed scanty acid-fast bacilli, and he was started on antituberculosis (anti ...
Sudden irreversible hearing loss post COVID-19 - BMJ Case Reports
Sudden onset sensorineural hearing loss (SSNHL) is frequently seen by otolaryngologists. The exact pathophysiology of the disease is still unknown, with the most likely causative factor being following a viral infection. Immediate steroids are the best treatment to improve prognosis. Despite a plethora of papers in the literature describing SSNHL, there are only a …
Phenytoin toxicity - BMJ Case Reports
Phenytoin induces gingival hypertrophy, causes cerebellar atrophy, and alters vitamin D and thyroid hormone (TH) homeostasis (figure 2, illustrated by AA, one of the authors).1 The association between long-term anticonvulsant therapy and rickets/osteomalacia was first described back in the 1960s.Phenytoin interferes with vitamin D metabolism at multiple steps.
Multiple and superimposed Mongolian spots | BMJ Case Reports
A 3-week-old Asian male newborn (42 weeks gestation, normal spontaneous vaginal delivery) presented for evaluation of multiple congenital greyish-blue macules. Dermatological examination showed a large grey to light-grey patch with undefined edges involving the sacrococcygeal and gluteal areas (size 9×6 cm); within this lesion, a superimposed, dark-blue, coin-shaped spot was observed (figure ...
Haemophagocytic lymphohistiocytosis (HLH) in an adult following ...
Investigations. Initial laboratory testing showed pancytopenia (white cell count 1.29 x 10 9 /L, haemoglobin 12.0 g/dL, platelets 89 x 10 9 /L). He had significantly elevated inflammatory markers (D-dimer 25 375 ng/mL and ferritin 19 350 ng/mL).
Fatal methaemoglobinemia due to intentional sodium nitrite …
Although unintentional sodium nitrite poisoning has been previously reported from home-cured meats and contaminated well-water, intentional ingestion of sodium nitrite for suicide has been increasingly reported.6–10 One case series of five patients with methaemoglobinemia in New York identified improperly labelled sodium nitrite salt as the culprit, with measured levels of sodium nitrite in ...