Video: Examining Proteasome Assembly with Recombinant Archaeal Proteasomes and Nondenaturing PAGE: The Case for a Combined Approach
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The 19 S subunit of the proteasome contains 6 subunits that are... | Filo
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The 26S proteasome going through several conformations after being activated. The ribbon structure of the protein chain is shown in between.
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SOLVED:In eukaryotes, the 20S proteasome component in conjunction with the 19 S component degrades ubiquitinated proteins with the hydrolysis of a molecule of ATP. Archaea lack ubiquitin and the 26 S proteasome but do contain a 20 S proteasome. Some archaea also contain an ATPase that is homologous to the ATPases of the eukaryotic 19S component. This archaeal ATPase activity was isolated as a 650 -kDa complex (called PAN) from the archaeon Thermoplasma, and experiments were performed to determin
SOLVED:In eukaryotes, the 20S proteasome component in conjun…
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